The well known advantages of biocatalysis with excellent chemoselectivity, enantioselectivity, and mild reaction conditions render biocatalysis as a feasible alternative for new processes in the chemical industry. However, a key issue is the limitation implied by the use of aqueous systems. Water is rarely a good solvent for the substrate at hand, limiting productivity of the possible processes. Moreover, water may interfere with other reaction steps and/or downstream processing.
Non-aqueous or non-conventional reaction media, such as organic solvents, ionic liquids or supercritical fluids provide a potential solution.
The course covers topics on relevant classes of biocatalysts, on properties of non-conventional media, and on methods and tools to analyse and integrate biocatalysts in non-conventional media for suitable processes.
overview